Isaac M. – BASIS Chandler

BASIS Chandler Senior Isaac M.

Metalloproteins - Expanding the "Worker" Molecule of the Human Body

Project/blog link: Metalloproteins - Expanding the "Worker" Molecule of the Human Body
BASIS Advisor: Mr. Matthew Cole
Internship location: ASU
Onsite Mentor: Dr. Jeremy Mills, Assistant Professor, School of Molecular Sciences

Project Abstract

Metalloproteins are proteins that contain a metal ion cofactor and compose between a quarter and half of all proteins in the human body. This metal cofactor typically dictates the protein’s function and influences a protein to complete tasks varying from oxygen transportation to signal transduction, like the “fight or flight” reflex. In addition to making up a significant amount of the body’s proteins, metalloproteins are relatively easy to design and implement in biological/cellular models. The Mills Lab at ASU Biodesign aims to increase our understanding of metalloprotein functionality and further develop these biological “worker” molecules to broaden their applicability. My research at this lab works to form specific molecules and analyze the structures and functions of the created compounds. To provide further education on proteomics and amino acids for the next generation of scientists, I am also working to develop a supplemental educational tool for biology students using Foldit software.

Metalloproteins - Expanding the "Worker" Molecule of the Human Body